Hydrochloric Acid → N-(4-(2-(1,4-dioxaspiro[4.5]decan-8-yl)thieno[3,2-b]pyridin-7-yloxy)-3-fluorophenyl)-2-(4-fluorophenyl)-3-oxo-2,3-dihydropyridazine-4-carboxamide
Reaction equation
[CH2:47]([N:48]=[C:49]=[N:50][CH2:51][CH2:52][CH2:53][N:54]([CH3:55])[CH3:56])[CH3:57].[CH2:68]([N:69]([CH:70]([CH3:71])[CH3:72])[CH:73]([CH3:74])[CH3:75])[CH3:76].[ClH:46].[F:29][c:30]1[cH:31][cH:32][c:33](-[n:36]2[n:37][cH:38][cH:39][c:40]([C:43](=[O:44])[OH:45])[c:41]2=[O:42])[cH:34][cH:35]1.[O:1]1[CH2:2][CH2:3][O:4][C:5]12[CH2:6][CH2:7][CH:8]([c:11]1[cH:12][c:13]3[n:14][cH:15][cH:16][c:17]([O:20][c:21]4[c:22]([F:28])[cH:23][c:24]([NH2:25])[cH:26][cH:27]4)[c:18]3[s:19]1)[CH2:9][CH2:10]2.[O:77]=[CH:78][N:79]([CH3:80])[CH3:81].[n:58]1([OH:59])[c:60]2[cH:61][cH:62][cH:63][cH:64][c:65]2[n:66][n:67]1>>[O:1]1[CH2:2][CH2:3][O:4][C:5]12[CH2:6][CH2:7][CH:8]([c:11]1[cH:12][c:13]3[n:14][cH:15][cH:16][c:17]([O:20][c:21]4[c:22]([F:28])[cH:23][c:24]([NH:25][C:43]([c:40]5[cH:39][cH:38][n:37][n:36](-[c:33]6[cH:32][cH:31][c:30]([F:29])[cH:35][cH:34]6)[c:41]5=[O:42])=[O:44])[cH:26][cH:27]4)[c:18]3[s:19]1)[CH2:9][CH2:10]2Participants
8
Reactant 7
Product 1
Sources & evidence
- ORD record
- ord-ce12293794e14d6786a68976bd0f76e9
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (4/10)
Reaction notes
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