Water → 3-((Trimethylsilyl)ethynyl)pyridin-2-amine
Reaction equation
[CH3:25][N:26]1[CH2:27][CH2:28][CH2:29][C:30]1=[O:31].[CH3:9][Si:10]([CH3:11])([CH3:12])[C:13]#[CH:14].[CH:15]([N:16]([CH2:17][CH3:18])[CH:19]([CH3:20])[CH3:21])([CH3:22])[CH3:23].[Cu:109][I:110].[NH2:1][c:2]1[n:3][cH:4][cH:5][cH:6][c:7]1[Br:8].[OH2:24].[cH:32]1[cH:33][cH:34][c:35]([P:36]([Pd:37]([P:38]([c:39]2[cH:40][cH:41][cH:42][cH:43][cH:44]2)([c:45]2[cH:46][cH:47][cH:48][cH:49][cH:50]2)[c:51]2[cH:52][cH:53][cH:54][cH:55][cH:56]2)([P:57]([c:58]2[cH:59][cH:60][cH:61][cH:62][cH:63]2)([c:64]2[cH:65][cH:66][cH:67][cH:68][cH:69]2)[c:70]2[cH:71][cH:72][cH:73][cH:74][cH:75]2)[P:76]([c:77]2[cH:78][cH:79][cH:80][cH:81][cH:82]2)([c:83]2[cH:84][cH:85][cH:86][cH:87][cH:88]2)[c:89]2[cH:90][cH:91][cH:92][cH:93][cH:94]2)([c:95]2[cH:96][cH:97][cH:98][cH:99][cH:100]2)[c:101]2[cH:102][cH:103][cH:104][cH:105][cH:106]2)[cH:107][cH:108]1>>[NH2:1][c:2]1[n:3][cH:4][cH:5][cH:6][c:7]1[C:14]#[C:13][Si:10]([CH3:9])([CH3:11])[CH3:12]Participants
8
Reactant 7
Product 1
Sources & evidence
- ORD record
- ord-949ad50cd1d743518d6beae6541d223a
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (4/10)
Reaction notes
Loading…