Potassium Cation → 2-(Trifluoromethyl)pyridine-3-carbonitrile

HRID 2139339Notes

Reaction equation

HRID 2139339 reaction equation
[CH3:12][N:13]([CH3:14])[CH:15]=[O:16].[CH3:33][N:34]1[CH2:35][CH2:36][CH2:37][C:38]1=[O:39].[Cu:30][I:31].[F-:1].[F:17][C:18]([F:19])([F:20])[Si:21]([CH3:22])([CH3:23])[CH3:24].[I:3][c:4]1[c:5]([C:6]#[N:7])[cH:8][cH:9][cH:10][n:11]1.[K+:2].[O:25]1[CH2:26][CH2:27][CH2:28][CH2:29]1.[OH2:32]>>[c:4]1([C:18]([F:17])([F:19])[F:20])[c:5]([C:6]#[N:7])[cH:8][cH:9][cH:10][n:11]1

Participants

10

Reactant 9

HCID 813Potassium CationHCID 962WaterHCID 6228DimethylformamideHCID 8028TetrahydrofuranHCID 13387N-methyl-2-pyrrolidoneHCID 24350Copper(1+) iodide; Copper(I) iodide; Cuprous iodide; Cuprous iodide (CuI)HCID 28179Fluoride IonHCID 552549(Trifluoromethyl)trimethylsilaneHCID 118064532-Iodonicotinonitrile

Product 1

HCID 269863872-(Trifluoromethyl)pyridine-3-carbonitrile

Sources & evidence

ORD record
ord-442d74e1660b4d4b89bc011190a4a00d
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (4/10)

Reaction notes

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