Hydrochloric Acid → Methyl 2-(4-fluorophenyl)-5-(2-methyl-5-(1-(pyridin-2-yl)cyclopropylcarbamoyl)phenyl)furo[2,3-b]pyridine-3-carboxylate

HRID 2149648Notes

Reaction equation

HRID 2149648 reaction equation
[CH3:81][CH2:82][O:83][C:84](=[O:85])[CH3:86].[CH:1]([N:2]([CH2:3][CH3:4])[CH:5]([CH3:6])[CH3:7])([CH3:8])[CH3:9].[ClH:64].[ClH:65].[F:34][c:35]1[cH:36][cH:37][c:38](-[c:41]2[c:42]([C:60](=[O:61])[O:62][CH3:63])[c:43]3[c:44]([n:45][cH:46][c:47](-[c:49]4[cH:50][c:51]([C:52](=[O:53])[OH:54])[cH:55][cH:56][c:57]4[CH3:58])[cH:48]3)[o:59]2)[cH:39][cH:40]1.[O:76]=[CH:77][N:78]([CH3:79])[CH3:80].[P-:10]([F:11])([F:12])([F:13])([F:14])([F:15])[F:16].[n:17]1([O:18][C:19]([N:20]([CH3:21])[CH3:22])=[N+:23]([CH3:24])[CH3:25])[c:26]2[n:27][cH:28][cH:29][cH:30][c:31]2[n:32][n:33]1.[n:66]1[c:67]([C:72]2([NH2:75])[CH2:73][CH2:74]2)[cH:68][cH:69][cH:70][cH:71]1>>[F:34][c:35]1[cH:36][cH:37][c:38](-[c:41]2[c:42]([C:60](=[O:61])[O:62][CH3:63])[c:43]3[c:44]([n:45][cH:46][c:47](-[c:49]4[cH:50][c:51]([C:52](=[O:54])[NH:75][C:72]5([c:67]6[n:66][cH:71][cH:70][cH:69][cH:68]6)[CH2:73][CH2:74]5)[cH:55][cH:56][c:57]4[CH3:58])[cH:48]3)[o:59]2)[cH:39][cH:40]1

Participants

9

Reactant 8

HCID 313Hydrochloric Acid2×HCID 6228DimethylformamideHCID 8857Ethyl AcetateHCID 9886HexafluorophosphateHCID 81531DiisopropylethylamineHCID 4641409(Dimethylamino)-N,N-dimethyl(3H-(1,2,3)triazolo(4,5-b)pyridin-3-yloxy)methaniminiumHCID 111054091-(Pyridin-2-yl)cyclopropanamineHCID 672175563-(2-(4-Fluorophenyl)-3-(methoxycarbonyl)furo[2,3-b]pyridin-5-yl)-4-methylbenzoic acid

Product 1

HCID 67217832Methyl 2-(4-fluorophenyl)-5-(2-methyl-5-(1-(pyridin-2-yl)cyclopropylcarbamoyl)phenyl)furo[2,3-b]pyridine-3-carboxylate

Sources & evidence

ORD record
ord-c1539c048be64625a0b872372988d74e
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (4/10)

Reaction notes

Loading…