Hydrochloric Acid → N-[4-[N-methyl-N-(tetrahydropyran-4-yl)aminomethyl]phenyl]-6-(4-methylphenyl)-2-methylquinoline-3-carboxamide

HRID 2152063Notes

Reaction equation

HRID 2152063 reaction equation
[CH2:33]([N:34]=[C:35]=[N:36][CH2:37][CH2:38][CH2:39][N:40]([CH3:41])[CH3:42])[CH3:43].[CH3:1][c:2]1[cH:3][cH:4][c:5](-[c:8]2[cH:9][c:10]3[cH:11][c:12]([C:19](=[O:20])[OH:21])[c:13]([CH3:18])[n:14][c:15]3[cH:16][cH:17]2)[cH:6][cH:7]1.[CH3:44][N:45]([CH:46]1[CH2:47][CH2:48][O:49][CH2:50][CH2:51]1)[CH2:52][c:53]1[cH:54][cH:55][c:56]([NH2:57])[cH:58][cH:59]1.[CH3:65][CH2:66][N:67]([CH2:68][CH3:69])[CH2:70][CH3:71].[ClH:32].[O:60]=[CH:61][N:62]([CH3:63])[CH3:64].[OH:22][n:23]1[c:24]2[cH:25][cH:26][cH:27][cH:28][c:29]2[n:30][n:31]1>>[CH3:1][c:2]1[cH:3][cH:4][c:5](-[c:8]2[cH:9][c:10]3[cH:11][c:12]([C:19](=[O:21])[NH:57][c:56]4[cH:55][cH:54][c:53]([CH2:52][N:45]([CH3:44])[CH:46]5[CH2:47][CH2:48][O:49][CH2:50][CH2:51]5)[cH:59][cH:58]4)[c:13]([CH3:18])[n:14][c:15]3[cH:16][cH:17]2)[cH:6][cH:7]1

Participants

8

Reactant 7

HCID 313Hydrochloric AcidHCID 6228DimethylformamideHCID 8471TriethylamineHCID 159081-Ethyl-3-(3'-dimethylaminopropyl)carbodiimideHCID 757711-HydroxybenzotriazoleHCID 9877845(4-Amino-benzyl)-methyl-(tetrahydro-pyran-4-yl)-amineHCID 229902036-(4-Methylphenyl)-2-methylquinoline-3-carboxylic acid

Product 1

HCID 18472458N-[4-[N-methyl-N-(tetrahydropyran-4-yl)aminomethyl]phenyl]-6-(4-methylphenyl)-2-methylquinoline-3-carboxamide

Sources & evidence

ORD record
ord-38fd77956402492c89026060ae29d364
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (4/10)

Reaction notes

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