Ammonium → 5-(3-Chloro-2-fluorobenzyl)-2-fluoro-4-methoxybenzoic acid methyl ester
Reaction equation
[Br-:34].[CH3:115][c:116]1[cH:117][cH:118][cH:119][cH:120][cH:121]1.[CH3:20][O:21][C:22]([c:23]1[c:24]([F:32])[cH:25][c:26]([O:30][CH3:31])[c:27]([Br:29])[cH:28]1)=[O:33].[CH3:47][N:48]1[CH2:49][CH2:50][CH2:51][C:52]1=[O:53].[Cl-:45].[Cl:35][c:36]1[c:37]([F:44])[c:38]([CH2:39][Zn+:40])[cH:41][cH:42][cH:43]1.[NH4+:46].[O:54]1[CH2:55][CH2:56][CH2:57][CH2:58]1.[O:61]=[C:62]([CH:63]=[CH:64][c:65]1[cH:66][cH:67][cH:68][cH:69][cH:70]1)[CH:71]=[CH:72][c:73]1[cH:74][cH:75][cH:76][cH:77][cH:78]1.[O:79]=[C:80]([CH:81]=[CH:82][c:83]1[cH:84][cH:85][cH:86][cH:87][cH:88]1)[CH:89]=[CH:90][c:91]1[cH:92][cH:93][cH:94][cH:95][cH:96]1.[O:97]=[C:98]([CH:99]=[CH:100][c:101]1[cH:102][cH:103][cH:104][cH:105][cH:106]1)[CH:107]=[CH:108][c:109]1[cH:110][cH:111][cH:112][cH:113][cH:114]1.[Pd:59].[Pd:60].[c:1]1([P:2]([c:3]2[cH:4][cH:5][cH:6][cH:7][cH:8]2)[c:9]2[cH:10][cH:11][cH:12][cH:13][cH:14]2)[cH:15][cH:16][cH:17][cH:18][cH:19]1>>[CH3:20][O:21][C:22]([c:23]1[c:24]([F:32])[cH:25][c:26]([O:30][CH3:31])[c:27]([CH2:39][c:38]2[c:37]([F:44])[c:36]([Cl:35])[cH:43][cH:42][cH:41]2)[cH:28]1)=[O:33]Participants
12
Reactant 11
Product 1
Sources & evidence
- ORD record
- ord-8ffb5ca6ad08415da82f11e0468cafe4
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (4/10)
Reaction notes
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