Hydrochloric Acid → 2-(N-Methylcarbamoyl)-1-[(6-methyl-4,5,6,7-tetrahydrothiazolo[5,4-c]pyridin-2-yl)carbonyl]-4-[(6-trimethylsilylethynylbenzo[b]thien-2-yl)sulfonyl]piperazine
Reaction equation
[CH2:44]([N:45]=[C:46]=[N:47][CH2:48][CH2:49][CH2:50][N:51]([CH3:52])[CH3:53])[CH3:54].[CH2:60]([Cl:61])[Cl:62].[CH3:1][NH:2][C:3](=[O:4])[CH:5]1[CH2:6][N:7]([S:11](=[O:12])(=[O:13])[c:14]2[cH:15][c:16]3[c:17]([s:18]2)[cH:19][c:20]([C:23]#[C:24][Si:25]([CH3:26])([CH3:27])[CH3:28])[cH:21][cH:22]3)[CH2:8][CH2:9][NH:10]1.[CH3:29][CH:30]1[CH2:31][c:32]2[c:33]([s:36][c:37]([C:39](=[O:40])[O-:41])[n:38]2)[CH2:34][NH:35]1.[CH3:55][N:56]([CH3:57])[CH:58]=[O:59].[ClH:43].[Li+:42]>>[CH3:1][NH:2][C:3](=[O:4])[CH:5]1[CH2:6][N:7]([S:11](=[O:12])(=[O:13])[c:14]2[cH:15][c:16]3[c:17]([s:18]2)[cH:19][c:20]([C:23]#[C:24][Si:25]([CH3:26])([CH3:27])[CH3:28])[cH:21][cH:22]3)[CH2:8][CH2:9][N:10]1[C:39]([c:37]1[s:36][c:33]2[c:32]([n:38]1)[CH2:31][CH:30]([CH3:29])[NH:35][CH2:34]2)=[O:40]Participants
8
Reactant 7
Product 1
Sources & evidence
- ORD record
- ord-fd881c15b4384b898f98c6741c654894
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (4/10)
Reaction notes
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