HRID2161283

反应详情

EQUATION

反应方程式

REACTANTS

反应物

HCID175

Acetate

C2H3O2-

2 次

HCID1140

Toluene

C7H8

HCID8471

Triethylamine

C6H15N

HCID11776

Triphenylphosphine

C18H15P

HCID66111

Trimethylsilylacetylene

C5H10Si

HCID83717

Copper iodide (CuI2)

CuI2

HCID105144

Palladium(2+)

Pd+2

HCID2763163

4-chloro-3-iodopyridine

C5H3ClIN

PRODUCTS

产物

HCID46318158

4-Chloro-3-[(trimethylsilyl)ethynyl]pyridine

C10H12ClNSi

来源与证据

来源类型: Open Reaction Database
ORD记录: ord-b4312c128df14d97a3c2d50b0a785995
来源数据集: Training data from https://doi.org/10.1039/C8SC04228D (4/10)
DOI: 10.1039/C8SC04228D
来源说明: Training data from https://doi.org/10.1039/C8SC04228D (4/10)

反应SMILES

[CH3:28][CH2:29][N:30]([CH2:31][CH3:32])[CH2:33][CH3:34].[CH3:35][Si:36]([CH3:37])([CH3:38])[C:39]#[CH:40].[CH3:41][c:42]1[cH:43][cH:44][cH:45][cH:46][cH:47]1.[Cl:1][c:2]1[c:3]([I:8])[cH:4][n:5][cH:6][cH:7]1.[Cu:48]([I:49])[I:50].[O-:52][C:53]([CH3:54])=[O:55].[O-:56][C:57]([CH3:58])=[O:59].[Pd+2:51].[c:9]1([P:10]([c:11]2[cH:12][cH:13][cH:14][cH:15][cH:16]2)[c:17]2[cH:18][cH:19][cH:20][cH:21][cH:22]2)[cH:23][cH:24][cH:25][cH:26][cH:27]1>>[Cl:1][c:2]1[c:3]([C:40]#[C:39][Si:36]([CH3:35])([CH3:37])[CH3:38])[cH:4][n:5][cH:6][cH:7]1