Potassium Cation → Ethyl 1-benzylpiperidine-4-carboxylate

HRID 2161622Notes

Reaction equation

HRID 2161622 reaction equation
[Br:1][CH2:2][c:3]1[cH:4][cH:5][cH:6][cH:7][cH:8]1.[K+:20].[K+:21].[NH:9]1[CH2:10][CH2:11][CH:12]([C:13](=[O:14])[O:15][CH2:16][CH3:17])[CH2:18][CH2:19]1.[O-:22][C:23]([O-:24])=[O:25].[O:27]=[CH:28][N:29]([CH3:30])[CH3:31].[OH2:26]>>[CH2:2]([c:3]1[cH:4][cH:5][cH:6][cH:7][cH:8]1)[N:9]1[CH2:10][CH2:11][CH:12]([C:13](=[O:14])[O:15][CH2:16][CH3:17])[CH2:18][CH2:19]1

Participants

7

Reactant 6

HCID 813Potassium Cation2×HCID 962WaterHCID 6228DimethylformamideHCID 7498Benzyl BromideHCID 19660Carbonate IonHCID 70770Ethyl 4-piperidinecarboxylate

Product 1

HCID 90423Ethyl 1-benzylpiperidine-4-carboxylate

Sources & evidence

ORD record
ord-f8c73d861d534ef39c1d42131e90776a
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (4/10)

Reaction notes

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