Dimethylamine, hydrochloride → HCID 20499838, compound

HRID 2166609Notes

Reaction equation

HRID 2166609 reaction equation
[O:1]1[CH:6]([C:7]([OH:9])=[O:8])[CH:2]1[C:3]([OH:5])=O.[CH2:10]([K])[CH3:11].C(Cl)(=O)C(Cl)=O.Cl.[CH3:20][NH:21][CH3:22]>C(N(CC)CC)C>[CH3:20][N:21]([CH3:22])[C:3](=[O:5])[CH:2]1[O:1][CH:6]1[C:7]([O:9][CH2:10][CH3:11])=[O:8]

Participants

5

Reactant 3

HCID 10473Dimethylamine, hydrochlorideHCID 65578Oxalyl chlorideHCID 178461626HCID 178461626, compound

Product 1

HCID 20499838HCID 20499838, compoundYield 39.6%

Reagents, catalysts & solvents 1

HCID 8471TriethylamineSolvent

Procedure

Following the procedure of Example 53, monoethyl potassium epoxysuccinate (1.0 g) was successively treated with oxalyl chloride (0.75 g) and a mixture of dimethylamine hydrochloride (1.23 g) and triethylamine (2.04 g) to give 0.37 g of ethyl N,N-dimethyl-2,3-epoxysuccinamate (Compound No. 85) as colorless oil.

Sources & evidence

ORD record
ord-bb325c0265f3493c8c8b19bc2f20972f
Source dataset
uspto-grants-1983_06
Patent number
US04387238

Reaction notes

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