Butyl iodide → HCID 22391791, compound

HRID 2271086Notes

Reaction equation

HRID 2271086 reaction equation
C([N:5]([CH:10]1[C:16]2[CH:17]=[C:18]([N+:21]([O-:23])=[O:22])[CH:19]=[CH:20][C:15]=2[O:14][CH2:13][CH2:12][CH2:11]1)[S:6]([CH3:9])(=[O:8])=[O:7])CCC.[H-].[Na+].ICCCC>CN(C=O)C>[CH3:9][S:6]([NH:5][CH:10]1[C:16]2[CH:17]=[C:18]([N+:21]([O-:23])=[O:22])[CH:19]=[CH:20][C:15]=2[O:14][CH2:13][CH2:12][CH2:11]1)(=[O:7])=[O:8]

Participants

5

Reactant 3

HCID 10962Butyl iodideHCID 24758Sodium hydrideHCID 9906051HCID 9906051, compound

Product 1

HCID 22391791HCID 22391791, compound

Reagents, catalysts & solvents 1

HCID 6228DimethylformamideSolvent

Procedure

From 0.5 g of 5-methylsulfonylamino-7-nitro-2,3,4,5-tetrahydro-1-benzoxepine 0.6 g of 5-(N-butyl-N-methylsulfonylamino)-7-nitro-2,3,4,5-tetrahydro-1-benzoxepine were obtained by reaction with sodium hydride and iodobutane in DMF analogously to Example 11, m.p. 96-98° C.

Sources & evidence

ORD record
ord-06af66a4d958499ebb8631e427021587
Source dataset
uspto-grants-2001_12
Patent number
US06333349B1

Reaction notes

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