反应详情

A mixture of 10 g of 4-aminomethylbenzoic acid, 14.5 g of carbethoxyphthalimide, 9.2 ml of triethylamine and 140 ml of tetrahydrofuran is maintained for 72 hours at reflux temperature. The precipitate formed is isolated at room temperature; after washing with an aqueous acidic solution and drying, 14.5 g of product are obtained. M.p.=264° C.

1. temperatureis maintained for 72 hours
2. temperatureat reflux temperature
3. customThe precipitate formed
4. customis isolated at room temperature
5. washafter washing with an aqueous acidic solution
6. customdrying