Bromide ion → 2-Ethyl-6-methylisonicotinic acid tert-butyl ester
Reaction equation
[Br-:1].[C:9]([CH3:10])([CH3:11])([CH3:12])[O:13][C:14]([c:15]1[cH:16][c:17]([Cl:22])[n:18][c:19]([CH3:21])[cH:20]1)=[O:23].[CH2:29]1[O:30][CH2:31][CH2:32][CH2:33]1.[CH2:2]([CH3:3])[Mg+:4].[CH2:5]([Br:6])[CH3:7].[CH3:24][CH2:25][O:26][CH2:27][CH3:28].[CH3:34][N:35]1[CH2:36][CH2:37][CH2:38][C:39]1=[O:40].[Mg:8]>>[CH2:2]([CH3:3])[c:17]1[cH:16][c:15]([C:14]([O:13][C:9]([CH3:10])([CH3:11])[CH3:12])=[O:23])[cH:20][c:19]([CH3:21])[n:18]1Participants
9
Reactant 8
Product 1
Sources & evidence
- ORD record
- ord-3e328b0b215a4338a63d3a4d4c0e1262
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (10/10)
Reaction notes
Loading…