Tetrahydrofuran → Benzyl 4-(2-hydroxyethyl)piperidine-1-carboxylate

HRID 2316181Notes

Reaction equation

HRID 2316181 reaction equation
[CH2:10]1[O:11][CH2:12][CH2:13][CH2:14]1.[CH3:35][CH2:36][O:37][C:38](=[O:39])[CH3:40].[CH:15]([N:16]([CH:17]([CH3:18])[CH3:19])[CH2:20][CH3:21])([CH3:22])[CH3:23].[Cl:24][C:25](=[O:26])[O:27][CH2:28][c:29]1[cH:30][cH:31][cH:32][cH:33][cH:34]1.[NH:1]1[CH2:2][CH2:3][CH:4]([CH2:7][CH2:8][OH:9])[CH2:5][CH2:6]1>>[N:1]1([C:25](=[O:26])[O:27][CH2:28][c:29]2[cH:30][cH:31][cH:32][cH:33][cH:34]2)[CH2:2][CH2:3][CH:4]([CH2:7][CH2:8][OH:9])[CH2:5][CH2:6]1

Participants

6

Reactant 5

HCID 8028TetrahydrofuranHCID 8857Ethyl AcetateHCID 10387Benzyl chloroformateHCID 739534-PiperidineethanolHCID 81531Diisopropylethylamine

Product 1

HCID 13971210Benzyl 4-(2-hydroxyethyl)piperidine-1-carboxylate

Sources & evidence

ORD record
ord-3ab495e6d38b4006a414873e3b721355
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (10/10)

Reaction notes

Loading…