Methanol → HCID 58486771, compound

HRID 2316580Notes

Reaction equation

HRID 2316580 reaction equation
[Br:12][c:13]1[c:14](-[c:22]2[n:23][cH:24][c:25]([NH2:28])[n:26][cH:27]2)[cH:15][c:16]2[c:17]([cH:21]1)[O:18][CH2:19][O:20]2.[CH3:38][N:39]([c:40]1[cH:41][cH:42][n:43][cH:44][cH:45]1)[CH3:46].[CH3:55][OH:56].[CH:29]([N:30]([CH2:31][CH3:32])[CH:33]([CH3:34])[CH3:35])([CH3:36])[CH3:37].[Cl:47][CH2:48][Cl:49].[F:1][c:2]1[c:3]([C:4](=[O:5])[Cl:6])[c:7]([F:11])[cH:8][cH:9][cH:10]1.[Li+:57].[O:50]1[CH2:51][CH2:52][CH2:53][CH2:54]1.[OH-:58]>>[F:1][c:2]1[c:3]([C:4](=[O:5])[NH:28][c:25]2[cH:24][n:23][c:22](-[c:14]3[c:13]([Br:12])[cH:21][c:17]4[c:16]([cH:15]3)[O:20][CH2:19][O:18]4)[cH:27][n:26]2)[c:7]([F:11])[cH:8][cH:9][cH:10]1

Participants

10

Reactant 9

HCID 887MethanolHCID 961HydroxideHCID 6344DichloromethaneHCID 8028TetrahydrofuranHCID 142844-(Dimethylamino)pyridineHCID 28486Lithium ionHCID 81531DiisopropylethylamineHCID 874382,6-Difluorobenzoyl chlorideHCID 58487378HCID 58487378, compound

Product 1

HCID 58486771HCID 58486771, compound

Sources & evidence

ORD record
ord-8f1cca3d21fe4f59b7742601cf3104c2
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (10/10)

Reaction notes

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