Hydrochloric Acid → N-biphenyl-4-yl-3-[4-(4-chloro-2,5-difluoro-benzoyl)-piperazin-1-yl]-3-oxo-propionamide
Reaction equation
[CH3:32][CH2:33][N:34]=[C:35]=[N:36][CH2:37][CH2:38][CH2:39][N:40]([CH3:41])[CH3:42].[CH:11]([N:12]([CH2:13][CH3:14])[CH:15]([CH3:16])[CH3:17])([CH3:18])[CH3:19].[Cl:20][c:21]1[cH:22][c:23]([F:31])[c:24]([C:25](=[O:26])[OH:27])[cH:28][c:29]1[F:30].[ClH:43].[ClH:44].[O:69]=[CH:70][N:71]([CH3:72])[CH3:73].[OH2:74].[OH:1][n:2]1[c:3]2[c:4]([cH:5][cH:6][cH:7][cH:8]2)[n:9][n:10]1.[c:45]1(-[c:63]2[cH:64][cH:65][cH:66][cH:67][cH:68]2)[cH:46][cH:47][c:48]([NH:51][C:52]([CH2:53][C:54]([N:55]2[CH2:56][CH2:57][NH:58][CH2:59][CH2:60]2)=[O:61])=[O:62])[cH:49][cH:50]1>>[Cl:20][c:21]1[cH:22][c:23]([F:31])[c:24]([C:25](=[O:27])[N:58]2[CH2:57][CH2:56][N:55]([C:54]([CH2:53][C:52]([NH:51][c:48]3[cH:47][cH:46][c:45](-[c:63]4[cH:64][cH:65][cH:66][cH:67][cH:68]4)[cH:50][cH:49]3)=[O:62])=[O:61])[CH2:60][CH2:59]2)[cH:28][c:29]1[F:30]Participants
9
Reactant 8
Product 1
Sources & evidence
- ORD record
- ord-85f56e9c34064fd99050ef4a0db40748
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (10/10)
Reaction notes
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