Tetrahydrofuran → 4-(3,5-Dioxo-5-pyridin-4-ylpentyl)piperidine-1-carboxylic acid tert-butyl ester
Reaction equation
[C:13]([CH3:14])([CH3:15])([CH3:16])[O:17][C:18](=[O:19])[N:20]1[CH2:21][CH2:22][CH:23]([CH2:26][CH2:27][C:28](=[O:29])[OH:30])[CH2:24][CH2:25]1.[C:1]([n:2]1[cH:3][cH:4][n:5][cH:6]1)([n:7]1[cH:8][cH:9][n:10][cH:11]1)=[O:12].[C:31]([CH3:32])(=[O:33])[c:34]1[cH:35][cH:36][n:37][cH:38][cH:39]1.[CH2:48]1[O:49][CH2:50][CH2:51][CH2:52]1.[CH3:41][CH:42]([N-:43][CH:44]([CH3:45])[CH3:46])[CH3:47].[CH3:53][CH2:54][O:55][C:56]([CH3:57])=[O:58].[Li+:40]>>[C:13]([CH3:14])([CH3:15])([CH3:16])[O:17][C:18](=[O:19])[N:20]1[CH2:21][CH2:22][CH:23]([CH2:26][CH2:27][C:28](=[O:30])[CH2:32][C:31](=[O:33])[c:34]2[cH:35][cH:36][n:37][cH:38][cH:39]2)[CH2:24][CH2:25]1Participants
8
Reactant 7
Product 1
Sources & evidence
- ORD record
- ord-8cc188177ad64a7897525dd163b50636
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (10/10)
Reaction notes
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