Water → HCID 57908178, compound

HRID 2323737Notes

Reaction equation

HRID 2323737 reaction equation
[C:17](#[CH:18])[CH:19]1[CH2:20][CH2:21][CH2:22]1.[CH2:30]1[O:31][CH2:32][CH2:33][CH2:34]1.[CH3:23][CH2:24][N:25]([CH2:26][CH3:27])[CH2:28][CH3:29].[Cl:1][c:2]1[cH:3][c:4]([I:16])[c:5]([NH:8][C:9]([O:10][C:11]([CH3:12])([CH3:13])[CH3:14])=[O:15])[cH:6][n:7]1.[Cu:77][I:78].[OH2:35].[Pd:36]([Cl:37])[Cl:38].[c:39]1([P:40]([c:41]2[cH:42][cH:43][cH:44][cH:45][cH:46]2)[c:47]2[cH:48][cH:49][cH:50][cH:51][cH:52]2)[cH:53][cH:54][cH:55][cH:56][cH:57]1.[c:58]1([P:59]([c:60]2[cH:61][cH:62][cH:63][cH:64][cH:65]2)[c:66]2[cH:67][cH:68][cH:69][cH:70][cH:71]2)[cH:72][cH:73][cH:74][cH:75][cH:76]1>>[Cl:1][c:2]1[cH:3][c:4]([C:18]#[C:17][CH:19]2[CH2:20][CH2:21][CH2:22]2)[c:5]([NH:8][C:9]([O:10][C:11]([CH3:12])([CH3:13])[CH3:14])=[O:15])[cH:6][n:7]1

Participants

9

Reactant 8

HCID 962WaterHCID 8028TetrahydrofuranHCID 8471TriethylamineHCID 11776Triphenylphosphine2×HCID 24290Palladium ChlorideHCID 24350Copper(1+) iodide; Copper(I) iodide; Cuprous iodide; Cuprous iodide (CuI)HCID 142749EthynylcyclobutaneHCID 53415320tert-Butyl (6-chloro-4-iodopyridin-3-yl)carbamate

Product 1

HCID 57908178HCID 57908178, compound

Sources & evidence

ORD record
ord-b9878d996b8645a5a05511b5b1a3d173
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (10/10)

Reaction notes

Loading…