Triethylamine → Dibenzyl-[1-(4-trimethylsilanylethynylphenyl)-cyclopropyl]-amine

HRID 2324312Notes

Reaction equation

HRID 2324312 reaction equation
[CH2:1]([c:2]1[cH:3][cH:4][cH:5][cH:6][cH:7]1)[N:8]([C:9]1([c:12]2[cH:13][cH:14][c:15]([Br:18])[cH:16][cH:17]2)[CH2:10][CH2:11]1)[CH2:19][c:20]1[cH:21][cH:22][cH:23][cH:24][cH:25]1.[CH3:26][Si:27]([CH3:28])([CH3:29])[C:30]#[CH:31].[CH3:32][CH2:33][N:34]([CH2:35][CH3:36])[CH2:37][CH3:38].[Cu:39][I:40].[Pd:41]([Cl:42])[Cl:43].[c:44]1([P:45]([c:46]2[cH:47][cH:48][cH:49][cH:50][cH:51]2)[c:52]2[cH:53][cH:54][cH:55][cH:56][cH:57]2)[cH:58][cH:59][cH:60][cH:61][cH:62]1.[c:63]1([P:64]([c:65]2[cH:66][cH:67][cH:68][cH:69][cH:70]2)[c:71]2[cH:72][cH:73][cH:74][cH:75][cH:76]2)[cH:77][cH:78][cH:79][cH:80][cH:81]1>>[CH2:1]([c:2]1[cH:3][cH:4][cH:5][cH:6][cH:7]1)[N:8]([C:9]1([c:12]2[cH:13][cH:14][c:15]([C:31]#[C:30][Si:27]([CH3:26])([CH3:28])[CH3:29])[cH:16][cH:17]2)[CH2:10][CH2:11]1)[CH2:19][c:20]1[cH:21][cH:22][cH:23][cH:24][cH:25]1

Participants

7

Reactant 6

HCID 8471TriethylamineHCID 11776Triphenylphosphine2×HCID 24290Palladium ChlorideHCID 24350Copper(1+) iodide; Copper(I) iodide; Cuprous iodide; Cuprous iodide (CuI)HCID 66111TrimethylsilylacetyleneHCID 22568917Dibenzyl-[1-(4-bromophenyl)-cyclopropyl]-amine

Product 1

HCID 22568993Dibenzyl-[1-(4-trimethylsilanylethynylphenyl)-cyclopropyl]-amine

Sources & evidence

ORD record
ord-8f31a798372f43299a5d164ba7da41a6
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (10/10)

Reaction notes

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