Chloride → (1,1'-Biphenyl)-2-carboxylic acid, 4'-methyl-, methyl ester
Reaction equation
[Br:6][c:7]1[cH:8][cH:9][c:10]([CH3:13])[cH:11][cH:12]1.[CH3:25][CH2:26][CH2:27][CH2:28][CH2:29][CH3:30].[Cl-:36].[Cl-:38].[I:14][c:15]1[c:16]([C:17](=[O:18])[O:19][CH3:20])[cH:21][cH:22][cH:23][cH:24]1.[Li:1][CH2:2][CH2:3][CH2:4][CH3:5].[O:31]1[CH2:32][CH2:33][CH2:34][CH2:35]1.[Zn+2:37].[cH:39]1[cH:40][cH:41][c:42]([P:43]([Pd:44]([P:45]([c:46]2[cH:47][cH:48][cH:49][cH:50][cH:51]2)([c:52]2[cH:53][cH:54][cH:55][cH:56][cH:57]2)[c:58]2[cH:59][cH:60][cH:61][cH:62][cH:63]2)([P:64]([c:65]2[cH:66][cH:67][cH:68][cH:69][cH:70]2)([c:71]2[cH:72][cH:73][cH:74][cH:75][cH:76]2)[c:77]2[cH:78][cH:79][cH:80][cH:81][cH:82]2)[P:83]([c:84]2[cH:85][cH:86][cH:87][cH:88][cH:89]2)([c:90]2[cH:91][cH:92][cH:93][cH:94][cH:95]2)[c:96]2[cH:97][cH:98][cH:99][cH:100][cH:101]2)([c:102]2[cH:103][cH:104][cH:105][cH:106][cH:107]2)[c:108]2[cH:109][cH:110][cH:111][cH:112][cH:113]2)[cH:114][cH:115]1>>[c:7]1(-[c:15]2[c:16]([C:17](=[O:18])[O:19][CH3:20])[cH:21][cH:22][cH:23][cH:24]2)[cH:8][cH:9][c:10]([CH3:13])[cH:11][cH:12]1Participants
9
Sources & evidence
- ORD record
- ord-f9b94aaa5ec34a01ae2d89a2e7948903
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (10/10)
Reaction notes
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