Dimethylformamide → 5-(2-(Trimethylsilyl)ethynyl)pyridin-2-amine
Reaction equation
[CH3:15][CH2:16][N:17]([CH2:18][CH3:19])[CH2:20][CH3:21].[CH3:9][Si:10]([CH3:11])([CH3:12])[C:13]#[CH:14].[I-:41].[NH2:1][c:2]1[n:3][cH:4][c:5]([Br:8])[cH:6][cH:7]1.[O:42]=[CH:43][N:44]([CH3:45])[CH3:46].[Pd:47]([Cl:48])[Cl:49].[c:22]1([P:23]([c:24]2[cH:25][cH:26][cH:27][cH:28][cH:29]2)[c:30]2[cH:31][cH:32][cH:33][cH:34][cH:35]2)[cH:36][cH:37][cH:38][cH:39][cH:40]1.[c:50]1([P:51]([c:52]2[cH:53][cH:54][cH:55][cH:56][cH:57]2)[c:58]2[cH:59][cH:60][cH:61][cH:62][cH:63]2)[cH:64][cH:65][cH:66][cH:67][cH:68]1.[c:69]1([P:70]([c:71]2[cH:72][cH:73][cH:74][cH:75][cH:76]2)[c:77]2[cH:78][cH:79][cH:80][cH:81][cH:82]2)[cH:83][cH:84][cH:85][cH:86][cH:87]1>>[NH2:1][c:2]1[n:3][cH:4][c:5]([C:14]#[C:13][Si:10]([CH3:9])([CH3:11])[CH3:12])[cH:6][cH:7]1Participants
8
Sources & evidence
- ORD record
- ord-1429d46fc01e45a6ad6ea0d09a7c7124
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (10/10)
Reaction notes
Loading…