Tetrahydrofuran → 1-Benzyl 4-ethyl piperidine-1,4-dicarboxylate

HRID 2341676Notes

Reaction equation

HRID 2341676 reaction equation
[C:19]([O:20][CH2:21][c:22]1[cH:23][cH:24][cH:25][cH:26][cH:27]1)(=[O:28])[Cl:29].[CH2:1]([CH3:2])[O:3][C:4](=[O:5])[CH:6]1[CH2:7][CH2:8][NH:9][CH2:10][CH2:11]1.[CH3:12][CH2:13][N:14]([CH2:15][CH3:16])[CH2:17][CH3:18].[O:30]1[CH2:31][CH2:32][CH2:33][CH2:34]1>>[CH2:1]([CH3:2])[O:3][C:4](=[O:5])[CH:6]1[CH2:7][CH2:8][N:9]([C:19]([O:20][CH2:21][c:22]2[cH:23][cH:24][cH:25][cH:26][cH:27]2)=[O:28])[CH2:10][CH2:11]1

Participants

5

Reactant 4

HCID 8028TetrahydrofuranHCID 8471TriethylamineHCID 10387Benzyl chloroformateHCID 70770Ethyl 4-piperidinecarboxylate

Product 1

HCID 152896721-Benzyl 4-ethyl piperidine-1,4-dicarboxylate

Sources & evidence

ORD record
ord-a0a056c7ebc549958a69ed9c94c7bd28
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (10/10)

Reaction notes

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