Triethylamine → 3-Bromo-5-phenylethynylpyridine

HRID 2343483Notes

Reaction equation

HRID 2343483 reaction equation
[Br:9][c:10]1[cH:11][n:12][cH:13][c:14]([Br:15])[cH:16]1.[CH3:17][CH2:18][N:19]([CH2:20][CH3:21])[CH2:22][CH3:23].[CH3:24][CH2:25][O:26][C:27](=[O:28])[CH3:29].[Cu:71][I:72].[Pd:30]([Cl:31])[Cl:32].[c:1]1([C:7]#[CH:8])[cH:2][cH:3][cH:4][cH:5][cH:6]1.[c:33]1([P:34]([c:35]2[cH:36][cH:37][cH:38][cH:39][cH:40]2)[c:41]2[cH:42][cH:43][cH:44][cH:45][cH:46]2)[cH:47][cH:48][cH:49][cH:50][cH:51]1.[c:52]1([P:53]([c:54]2[cH:55][cH:56][cH:57][cH:58][cH:59]2)[c:60]2[cH:61][cH:62][cH:63][cH:64][cH:65]2)[cH:66][cH:67][cH:68][cH:69][cH:70]1>>[c:1]1([C:7]#[C:8][c:14]2[cH:13][n:12][cH:11][c:10]([Br:9])[cH:16]2)[cH:2][cH:3][cH:4][cH:5][cH:6]1

Participants

8

Reactant 7

HCID 8471TriethylamineHCID 8857Ethyl AcetateHCID 10821PhenylacetyleneHCID 11776Triphenylphosphine2×HCID 24290Palladium ChlorideHCID 24350Copper(1+) iodide; Copper(I) iodide; Cuprous iodide; Cuprous iodide (CuI)HCID 693693,5-Dibromopyridine

Product 1

HCID 670476693-Bromo-5-phenylethynylpyridine

Sources & evidence

ORD record
ord-559230bc365248b0895b8d9c9dc785f4
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (10/10)

Reaction notes

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