反应详情

To a stirred mixture of about 39.7 g of about 50% sodium hydride, about 13.5 g of sodium iodide and about 208.58 g of tetradecylbromide in about 750 ml of dimethylformamide at about 0° C. was added a solution of about 125 g of ethyl p-hydroxybenzoate in about 400 ml of dimethylformamide over about 1/2 hour. The mixture was stirred at room temperature for about 67 hours and then poured into about 2 liters of water. The solid was collected, washed with water, mixed with hot (about 50° C.) ethyl acetate, washed with water and dried. The solvent was removed and the residue recrystallized from ethanol, giving about 144.57 g of the desired title compound, mp 34°-35° C.

1. customThe solid was collected
2. washwashed with water
3. additionmixed with hot (about 50° C.) ethyl acetate
4. washwashed with water
5. customdried
6. customThe solvent was removed
7. customthe residue recrystallized from ethanol