Methanesulfonic Acid → HCID 528718, compound

HRID 236025Notes

Reaction equation

HRID 236025 reaction equation
[CH3:1][C:2](O)([CH2:4][CH3:5])[CH3:3].CS(O)(=O)=O.[C:12](O[C:17](=O)[CH2:18][CH3:19])(=O)[CH2:13][CH3:14].[NH4+:21].[OH-].[O+]1[CH:28]=[CH:27][CH:26]=[CH:25][CH:24]=1>>[CH2:25]([C:26]1[C:4]([CH3:5])=[C:2]([CH3:3])[CH:1]=[C:17]([CH2:18][CH3:19])[N:21]=1)[CH3:24].[CH2:13]([C:12]1[CH:3]=[C:2]([CH2:4][CH3:5])[CH:1]=[C:28]([CH2:27][CH3:26])[N:21]=1)[CH3:14]

Participants

7

Reactant 5

HCID 6395Methanesulfonic AcidHCID 64052-Methyl-2-butanolHCID 14923Ammonium HydroxideHCID 31263Propionic anhydrideHCID 9548819Pyrylium

Product 2

HCID 528718HCID 528718, compoundHCID 3084917Pyridine, 2,4,6-triethyl-

Procedure

The procedure of Example 1-a was repeated for this synthesis. From 0.05 mole (5.4 ml) of 2-methyl-2-butanol, 0.1 mole (6.5 ml) of methanesulfonic acid and 0.4 mole of propionic anhydride, after treating with NH4OH the aqueous solution of pyrylium salts, 4.1 g (50%) were obtained of a mixture of 2,6-diethyl-3,4-dimethylpyridine and of 2,4,6-triethylpyridine in the respective proportions of 96% and 4%.

Workup

  1. customThe procedure of Example 1-a was repeated for this synthesis

Sources & evidence

ORD record
ord-530db13112be4063a39ebc104a0a74b6
Source dataset
uspto-grants-1987_02
Patent number
US04642359

Reaction notes

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