Hydrochloric Acid → HCID 21315534, compound

HRID 236878Notes

Reaction equation

HRID 236878 reaction equation
[C:1]([C:3]1[CH:8]=[CH:7][N:6]=[CH:5][CH:4]=1)#[N:2].[ClH:9].[CH:10]([C:12]1[CH:17]=[CH:16][CH:15]=[CH:14][N:13]=1)=[CH2:11]>C(O)(C)C>[ClH:9].[Cl-:9].[N:13]1[CH:14]=[CH:15][CH:16]=[CH:17][C:12]=1[CH2:10][CH2:11][N+:6]1[CH:7]=[CH:8][C:3]([C:1]#[N:2])=[CH:4][CH:5]=1

Participants

5

Reactant 3

HCID 313Hydrochloric AcidHCID 75064-CyanopyridineHCID 75212-Vinylpyridine

Product 1

HCID 21315534HCID 21315534, compound

Reagents, catalysts & solvents 1

HCID 3776IsopropanolSolvent3×

Conditions

Temperature
25 °C

Procedure

To 166.4 parts of 4-cyanopyridine in 500 cc of isopropanol was added 170 parts of a 15.9% solution of hydrogen chloride in isopropanol. To this was added 292 parts of 2-vinylpyridine in 500 cc of isopropanol, and the resulting mixture heated to reflux for 5.5 hours. The reaction was cooled to 25° C. and 261 parts of 1-[2-(2-pyridyl)ethyl]-4-cyanopyridinium chloride hydrochloride isolated on filtration.

Workup

  1. temperaturethe resulting mixture heated
  2. temperatureto reflux for 5.5 hours

Sources & evidence

ORD record
ord-d2e3df6f18d2475482f8a82788e707fb
Source dataset
uspto-grants-1979_06
Patent number
US04158093

Reaction notes

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