Methylamine → HCID 11689375, compound
Reaction equation
[NH2:1][C:2]1[C:10]([CH3:11])=[CH:9][CH:8]=[CH:7][C:3]=1[C:4]([OH:6])=O.[CH3:12][NH2:13].[CH:14](=O)[C:15]1[CH:20]=[CH:19][C:18]([O:21][CH3:22])=[CH:17][CH:16]=1.Cl[CH2:25][CH2:26][CH2:27]Br.[NH:29]1[CH2:33]C[CH2:31][CH2:30]1>>[CH3:12][N:13]1[C:4](=[O:6])[C:3]2[C:2](=[C:10]([CH3:11])[CH:9]=[CH:8][CH:7]=2)[N:1]=[C:14]1[C:15]1[CH:20]=[CH:19][C:18]([O:21][CH2:22][CH2:31][CH2:30][N:29]2[CH2:33][CH2:27][CH2:26][CH2:25]2)=[CH:17][CH:16]=1Participants
6
Procedure
The entitled compound was obtained according to the method of Example 1 but starting from 2-amino-3-methylbenzoic acid, methylamine, 4-anisaldehyde, 1-chloro-3-bromopropane and pyrrolidine.
Workup
- customThe entitled compound was obtained
Sources & evidence
- ORD record
- ord-1509632159964f47a739e145fe8ae719
- Source dataset
- uspto-grants-2011_06
- Patent number
- US07960394B2
Reaction notes
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