反应详情

温度

70 °C

To 4-amino-3-methoxyphenylboronic acid pinacol ester (24.08 mmol, 6 g) and charcoal (0.29 g) in ethyl acetate (50 ml), was added trichloromethyl chloroformate (48.2 mmol, 5.81 mL) and the mixture was stirred at 70° C. for two hours. After cooling to room temperature the solids were removed by filtration and the filtrate concentrated in vacuo to give 6.7 g of 2-(4-isocyanato-3-methoxyphenyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane.

1. temperatureAfter cooling to room temperature the solids
2. customwere removed by filtration
3. concentrationthe filtrate concentrated in vacuo