反应详情

4-Bromophenol (2 g, 0.0116 mol) in acetone (40 mL) was treated with potassium carbonate anhydrous (1.91 g, 1.2 equivalents) and benzyl bromide (1.44 mL, 1.05 equivalents). The reaction was refluxed under a nitrogen atmosphere. After 5-6 hours reflux, the reaction was cooled to room temperature and diluted with an equal volume of ethyl acetate. This solution was washed with water, dried over anhydrous magnesium sulfate and evaporated to dryness. A white fluffy solid was obtained. Yield=2.36 g (73%).

1. temperatureThe reaction was refluxed under a nitrogen atmosphere
2. temperatureAfter 5-6 hours reflux
3. washThis solution was washed with water
4. dry with materialdried over anhydrous magnesium sulfate
5. customevaporated to dryness
6. customA white fluffy solid was obtained