Bromide ion → 1-(Pyridin-2-yl)cyclopropanamine

HRID 284526Notes

Reaction equation

HRID 284526 reaction equation
[Br-:26].[CH2:27]([Mg+:28])[CH3:29].[CH2:9]([CH3:10])[O:11][CH2:12][CH3:13].[CH3:21][CH2:22][O:23][CH2:24][CH3:25].[CH3:30][CH:31]([CH3:32])[O-:33].[CH3:34][CH:35]([CH3:36])[O-:37].[CH3:38][CH:39]([CH3:40])[O-:41].[CH3:42][CH:43]([CH3:44])[O-:45].[ClH:18].[F:14][B:15]([F:16])[F:17].[N:1]#[C:2][c:3]1[cH:4][cH:5][cH:6][cH:7][n:8]1.[Na+:20].[O:47]1[CH2:48][CH2:49][CH2:50][CH2:51]1.[OH-:19].[Ti+4:46]>>[NH2:1][C:2]1([c:3]2[cH:4][cH:5][cH:6][cH:7][n:8]2)[CH2:9][CH2:10]1

Participants

12

Reactant 11

HCID 259Bromide ionHCID 313Hydrochloric AcidHCID 923Sodium ionHCID 961HydroxideHCID 3283Diethyl Ether2×HCID 6356Boron trifluorideHCID 7522Pyridine-2-carbonitrileHCID 8028TetrahydrofuranHCID 114942Titanium cation (4+)HCID 3260420Isopropanolate4×HCID 178461628HCID 178461628, compound

Product 1

HCID 111054091-(Pyridin-2-yl)cyclopropanamine

Sources & evidence

ORD record
ord-f7593626af404537931c3e8f6dda6efd
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (8/10)

Reaction notes

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