Hydrochloric Acid → 2-Amino-7-(4-fluoro-phenyl)-4-methyl-7,8-dihydro-6H-quinazolin-5-one O-(2-dimethylamino-ethyl)-oxime
Reaction equation
[CH3:25][N:26]([CH2:27][CH2:28][Cl:29])[CH3:30].[CH3:31][CH2:32][N:33]([CH2:34][CH3:35])[CH2:36][CH3:37].[CH3:43][CH2:44][O:45][C:46](=[O:47])[CH3:48].[ClH:24].[H-:22].[NH2:1][c:2]1[n:3][c:4]2[c:9]([c:10]([CH3:12])[n:11]1)[C:8](=[N:13][OH:14])[CH2:7][CH:6]([c:15]1[cH:16][cH:17][c:18]([F:21])[cH:19][cH:20]1)[CH2:5]2.[Na+:23].[O:38]=[CH:39][N:40]([CH3:41])[CH3:42]>>[NH2:1][c:2]1[n:3][c:4]2[c:9]([c:10]([CH3:12])[n:11]1)[C:8](=[N:13][O:14][CH2:28][CH2:27][N:26]([CH3:25])[CH3:30])[CH2:7][CH:6]([c:15]1[cH:16][cH:17][c:18]([F:21])[cH:19][cH:20]1)[CH2:5]2Participants
9
Reactant 8
Product 1
Sources & evidence
- ORD record
- ord-9676ee6dec5a468283f51b359a16f347
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (8/10)
Reaction notes
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