1,2-Dichloroethane → N-{[5-(4-bromophenyl)-5H-imidazo[2,1-a]isoindol-5-yl]methyl}cyclohexanecarboxamide

HRID 288500Notes

Reaction equation

HRID 288500 reaction equation
[CH2:23]([Cl:24])[CH2:25][Cl:26].[CH:27]([N:28]([CH2:29][CH3:30])[CH:31]([CH3:32])[CH3:33])([CH3:34])[CH3:35].[Cl-:1].[NH2:2][CH2:3][C:4]1([c:16]2[cH:17][cH:18][c:19]([Br:22])[cH:20][cH:21]2)[n:5]2[c:6]([nH+:13][cH:14][cH:15]2)-[c:7]2[cH:8][cH:9][cH:10][cH:11][c:12]21.[O:45]=[CH:46][N:47]([CH3:48])[CH3:49].[OH:36][C:37](=[O:38])[CH:39]1[CH2:40][CH2:41][CH2:42][CH2:43][CH2:44]1>>[NH:2]([CH2:3][C:4]1([c:16]2[cH:17][cH:18][c:19]([Br:22])[cH:20][cH:21]2)[n:5]2[c:6]([n:13][cH:14][cH:15]2)-[c:7]2[cH:8][cH:9][cH:10][cH:11][c:12]21)[C:37](=[O:36])[CH:39]1[CH2:40][CH2:41][CH2:42][CH2:43][CH2:44]1

Participants

7

Reactant 6

HCID 111,2-DichloroethaneHCID 312ChlorideHCID 6228DimethylformamideHCID 7413Cyclohexanecarboxylic acidHCID 81531DiisopropylethylamineHCID 178509336HCID 178509336, compound

Product 1

HCID 58415567N-{[5-(4-bromophenyl)-5H-imidazo[2,1-a]isoindol-5-yl]methyl}cyclohexanecarboxamide

Sources & evidence

ORD record
ord-4617fd77932a412980a6fa7407de600b
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (8/10)

Reaction notes

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