Acetate → Methyl 3-(pyridin-3-yl)acrylate

HRID 289383Notes

Reaction equation

HRID 289383 reaction equation
[Br:1][c:2]1[cH:3][n:4][cH:5][cH:6][cH:7]1.[C:8]([CH:9]=[CH2:10])(=[O:11])[O:12][CH3:13].[CH3:36][CH2:37][N:38]([CH2:39][CH3:40])[CH2:41][CH3:42].[CH:52]([Cl:53])([Cl:54])[Cl:55].[O-:44][C:45]([CH3:46])=[O:47].[O-:48][C:49]([CH3:50])=[O:51].[Pd+2:43].[c:14]1([CH3:15])[cH:16][cH:17][cH:18][cH:19][c:20]1[P:21]([c:22]1[cH:23][cH:24][cH:25][cH:26][c:27]1[CH3:28])[c:29]1[cH:30][cH:31][cH:32][cH:33][c:34]1[CH3:35]>>[c:2]1([CH:10]=[CH:9][C:8](=[O:11])[O:12][CH3:13])[cH:3][n:4][cH:5][cH:6][cH:7]1

Participants

8

Reactant 7

HCID 175Acetate2×HCID 6212ChloroformHCID 7294Methyl AcrylateHCID 8471TriethylamineHCID 122863-BromopyridineHCID 80271Tri-o-tolylphosphineHCID 105144Allyl(1,3-bis(2,6-diisopropylphenyl)imidazol-2-ylidene)chloropalladium(II)

Product 1

HCID 143845Methyl 3-(pyridin-3-yl)acrylate

Sources & evidence

ORD record
ord-2b2865a1a6034a799ce9c970ae606039
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (8/10)

Reaction notes

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