1,2-Dichloroethane → N-(5-bromopyridin-3-yl)propionamide

HRID 290435Notes

Reaction equation

HRID 290435 reaction equation
[CH2:16]([Cl:17])[CH2:18][Cl:19].[CH3:1][CH2:2][C:3]([OH:4])=[O:5].[CH3:29][N:30]1[CH2:31][CH2:32][O:33][CH2:34][CH2:35]1.[ClH:20].[NH2:21][c:22]1[cH:23][n:24][cH:25][c:26]([Br:28])[cH:27]1.[O:36]=[CH:37][N:38]([CH3:39])[CH3:40].[OH:6][n:7]1[c:8]2[c:9]([cH:10][cH:11][cH:12][cH:13]2)[n:14][n:15]1>>[CH3:1][CH2:2][C:3](=[O:5])[NH:21][c:22]1[cH:23][n:24][cH:25][c:26]([Br:28])[cH:27]1

Participants

8

Reactant 7

HCID 111,2-DichloroethaneHCID 313Hydrochloric AcidHCID 1032Propionic AcidHCID 6228DimethylformamideHCID 79724-MethylmorpholineHCID 757711-HydroxybenzotriazoleHCID 8176813-Amino-5-bromopyridine

Product 1

HCID 68737458N-(5-bromopyridin-3-yl)propionamide

Sources & evidence

ORD record
ord-10f002fce14943f0840925b29768a9b5
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (8/10)

Reaction notes

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