Ammonium → 1-[3-(6-Fluoro-1,2-benzisoxazol-3-yl)propyl]-4-(4-fluorophenyl)-4-hydroxypiperidine
Reaction equation
[Br:2][CH:3]([Br:4])[CH3:5].[Br:6][c:7]1[cH:8][cH:9][c:10]([F:13])[cH:11][cH:12]1.[Cl-:34].[F:14][c:15]1[cH:16][c:17]2[c:18]([c:19]([CH2:22][CH2:23][CH2:24][N:25]3[CH2:26][CH2:27][C:28](=[O:31])[CH2:29][CH2:30]3)[n:20][o:21]2)[cH:32][cH:33]1.[Mg:1].[NH4+:35].[O:36]1[CH2:37][CH2:38][CH2:39][CH2:40]1>>[c:7]1([C:28]2([OH:31])[CH2:27][CH2:26][N:25]([CH2:24][CH2:23][CH2:22][c:19]3[c:18]4[c:17]([cH:16][c:15]([F:14])[cH:33][cH:32]4)[o:21][n:20]3)[CH2:30][CH2:29]2)[cH:8][cH:9][c:10]([F:13])[cH:11][cH:12]1Participants
8
Reactant 7
Product 1
Sources & evidence
- ORD record
- ord-e8dc6d73dfad42ddb40c1389bbd7dca6
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (8/10)
Reaction notes
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