Acetate → 2-(4-Methylphenyl)thiophene

HRID 293041Notes

Reaction equation

[Br:10][c:11]1[s:12][cH:13][cH:14][cH:15]1.[Br:1][c:2]1[cH:3][cH:4][c:5]([CH3:8])[cH:6][cH:7]1.[C:40]([O-:41])(=[O:42])[CH3:43].[C:45]([O-:46])(=[O:47])[CH3:48].[CH2:35]1[O:36][CH2:37][CH2:38][CH2:39]1.[Mg:9].[Pd+2:44].[c:16]1([P:17]([c:18]2[cH:19][cH:20][cH:21][cH:22][cH:23]2)[c:24]2[cH:25][cH:26][cH:27][cH:28][cH:29]2)[cH:30][cH:31][cH:32][cH:33][cH:34]1>>[c:2]1(-[c:11]2[s:12][cH:13][cH:14][cH:15]2)[cH:3][cH:4][c:5]([CH3:8])[cH:6][cH:7]1

Participants

Reactant 7

HCID 175Acetate2×

HCID 78054-Bromotoluene

HCID 8028Tetrahydrofuran

HCID 11776Triphenylphosphine

HCID 138512-Bromothiophene

HCID 105144Allyl(1,3-bis(2,6-diisopropylphenyl)imidazol-2-ylidene)chloropalladium(II)

HCID 5462224Magnesium

Product 1

HCID 41284662-(4-Methylphenyl)thiophene

Sources & evidence

ORD record: ord-67f603cc6fb046e485731b0f3ee2ab6b
Source dataset: Training data from https://doi.org/10.1039/C8SC04228D (8/10)
DOI: 10.1039/C8SC04228D

Reaction notes

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