Dimethylformamide → N-[3-({2-[(cyclopropylcarbonyl)amino]imidazo[1,2-b]pyridazin-6-yl}oxy)phenyl]-3-methyl-1-(2,2,2-trifluoroethyl)-1H-pyrazole-5-carboxamide
Reaction equation
[CH3:1][c:2]1[n:3][n:4]([CH2:10][C:11]([F:12])([F:13])[F:14])[c:5]([C:7](=[O:8])[OH:9])[cH:6]1.[CH3:44][CH2:45][N:46]([CH2:47][CH3:48])[CH2:49][CH3:50].[CH3:56][N:57]([CH3:58])[CH:59]=[O:60].[Cl:15][C:16]([C:17]([Cl:18])=[O:19])=[O:20].[NH2:21][c:22]1[cH:23][c:24]([O:25][c:26]2[cH:27][cH:28][c:29]3[n:30]([n:31]2)[cH:32][c:33]([NH:35][C:36](=[O:37])[CH:38]2[CH2:39][CH2:40]2)[n:34]3)[cH:41][cH:42][cH:43]1.[O:51]1[CH2:52][CH2:53][CH2:54][CH2:55]1>>[CH3:1][c:2]1[n:3][n:4]([CH2:10][C:11]([F:12])([F:13])[F:14])[c:5]([C:7](=[O:9])[NH:21][c:22]2[cH:23][c:24]([O:25][c:26]3[cH:27][cH:28][c:29]4[n:30]([n:31]3)[cH:32][c:33]([NH:35][C:36](=[O:37])[CH:38]3[CH2:39][CH2:40]3)[n:34]4)[cH:41][cH:42][cH:43]2)[cH:6]1Participants
7
Reactant 6
Product 1
Sources & evidence
- ORD record
- ord-810432b948bc462a96cffa0c6341b645
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (8/10)
Reaction notes
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