Hydrochloric Acid → 1-(3-Amino-4-nitrophenyl)-piperidin-3-ol

HRID 296602Notes

Reaction equation

HRID 296602 reaction equation
[Cl:1][c:2]1[cH:3][cH:4][c:5]([N+:9](=[O:10])[O-:11])[c:6]([NH2:8])[cH:7]1.[ClH:12].[K+:20].[K+:21].[O-:22][C:23]([O-:24])=[O:25].[O:27]=[CH:28][N:29]([CH3:30])[CH3:31].[OH2:26].[OH:13][CH:14]1[CH2:15][NH:16][CH2:17][CH2:18][CH2:19]1>>[c:2]1([N:16]2[CH2:15][CH:14]([OH:13])[CH2:19][CH2:18][CH2:17]2)[cH:3][cH:4][c:5]([N+:9](=[O:10])[O-:11])[c:6]([NH2:8])[cH:7]1

Participants

8

Reactant 7

HCID 313Hydrochloric AcidHCID 813Potassium Cation2×HCID 962WaterHCID 6228DimethylformamideHCID 19660Carbonate IonHCID 232933-HydroxypiperidineHCID 742185-Chloro-2-nitroaniline

Product 1

HCID 98346111-(3-Amino-4-nitrophenyl)-piperidin-3-ol

Sources & evidence

ORD record
ord-de091d4f78554cb7b7cbe773ccf1d90f
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (8/10)

Reaction notes

Loading…