Dimethylformamide → Tert-butyl(2-chloro-5-methylphenoxy)dimethylsilane

HRID 300983Notes

Reaction equation

HRID 300983 reaction equation
[C:17]([CH3:18])([CH3:19])([CH3:20])[Si:21]([CH3:22])([CH3:23])[Cl:24].[CH3:10][CH2:11][N:12]([CH2:13][CH3:14])[CH2:15][CH3:16].[CH3:25][N:26]([c:27]1[cH:28][cH:29][n:30][cH:31][cH:32]1)[CH3:33].[Cl:1][c:2]1[c:3]([OH:9])[cH:4][c:5]([CH3:8])[cH:6][cH:7]1.[O:34]=[CH:35][N:36]([CH3:37])[CH3:38]>>[Cl:1][c:2]1[c:3]([O:9][Si:21]([C:17]([CH3:18])([CH3:19])[CH3:20])([CH3:22])[CH3:23])[cH:4][c:5]([CH3:8])[cH:6][cH:7]1

Participants

6

Reactant 5

HCID 6228DimethylformamideHCID 8471TriethylamineHCID 120082-Chloro-5-methylphenolHCID 142844-(Dimethylamino)pyridineHCID 28928tert-Butyldimethylsilyl chloride

Product 1

HCID 59803183Tert-butyl(2-chloro-5-methylphenoxy)dimethylsilane

Sources & evidence

ORD record
ord-f37b84e06d3d4426863b9428b58c230e
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (8/10)

Reaction notes

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