Hydrogen Peroxide → 1-[4-(4-Chlorophenoxy)phenyl]-3-(3-hydroxypropyl)-5-[3-(trifluoromethyl)phenyl]pyrrolidin-2-one
Reaction equation
[CH2:47]1[O:48][CH2:49][CH2:50][CH2:51]1.[CH3:52][CH2:53][O:54][C:55](=[O:56])[CH3:57].[CH:34]12[CH2:35][CH2:36][CH2:37][CH:38]([BH:39]1)[CH2:40][CH2:41][CH2:42]2.[Cl:1][c:2]1[cH:3][cH:4][c:5]([O:6][c:7]2[cH:8][cH:9][c:10]([N:13]3[C:14](=[O:31])[CH:15]([CH2:28][CH:29]=[CH2:30])[CH2:16][CH:17]3[c:18]3[cH:19][c:20]([C:24]([F:25])([F:26])[F:27])[cH:21][cH:22][cH:23]3)[cH:11][cH:12]2)[cH:32][cH:33]1.[Na+:44].[OH-:43].[OH:45][OH:46]>>[Cl:1][c:2]1[cH:3][cH:4][c:5]([O:6][c:7]2[cH:8][cH:9][c:10]([N:13]3[C:14](=[O:31])[CH:15]([CH2:28][CH2:29][CH2:30][OH:43])[CH2:16][CH:17]3[c:18]3[cH:19][c:20]([C:24]([F:25])([F:26])[F:27])[cH:21][cH:22][cH:23]3)[cH:11][cH:12]2)[cH:32][cH:33]1Participants
8
Reactant 7
Product 1
Sources & evidence
- ORD record
- ord-5d62d0def95f48669e09f29eed4a62f1
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (8/10)
Reaction notes
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