Dimethylformamide → 3-[4-(6-Amino-5-benzothiazol-2-ylpyridin-3-yl)-pyrazol-1-yl]-1-pyrrolidin-1-ylpropan-1-one
Reaction equation
[B-:32]([F:33])([F:34])([F:35])[F:36].[CH2:27]1[CH2:28][CH2:29][NH:30][CH2:31]1.[CH3:68][CH2:69][O:70][C:71]([CH3:72])=[O:73].[CH:54]([N:55]([CH2:56][CH3:57])[CH:58]([CH3:59])[CH3:60])([CH3:61])[CH3:62].[NH2:1][c:2]1[c:3](-[c:18]2[s:19][c:20]3[c:21]([n:22]2)[cH:23][cH:24][cH:25][cH:26]3)[cH:4][c:5](-[c:8]2[cH:9][n:10][n:11]([CH2:13][CH2:14][C:15](=[O:16])[OH:17])[cH:12]2)[cH:6][n:7]1.[O:63]=[CH:64][N:65]([CH3:66])[CH3:67].[n:37]1([O:38][C:39]([N:40]([CH3:41])[CH3:42])=[N+:43]([CH3:44])[CH3:45])[c:46]2[cH:47][cH:48][cH:49][cH:50][c:51]2[n:52][n:53]1>>[NH2:1][c:2]1[c:3](-[c:18]2[s:19][c:20]3[c:21]([n:22]2)[cH:23][cH:24][cH:25][cH:26]3)[cH:4][c:5](-[c:8]2[cH:9][n:10][n:11]([CH2:13][CH2:14][C:15](=[O:16])[N:30]3[CH2:29][CH2:28][CH2:27][CH2:31]3)[cH:12]2)[cH:6][n:7]1Participants
8
Reactant 7
Product 1
Sources & evidence
- ORD record
- ord-93e235f2702342efbec144fcc6542975
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (8/10)
Reaction notes
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