Hydrochloric Acid → 6-Phenyl-N-[1-(2,2,2-trifluoroethyl)piperidin-4-yl]nicotinamide
Reaction equation
[CH3:17][N:18]([CH3:19])[CH2:20][CH2:21][CH2:22][N:23]=[C:24]=[N:25][CH2:26][CH3:27].[CH3:50][N:51]1[CH2:52][CH2:53][O:54][CH2:55][CH2:56]1.[CH3:57][N:58]([CH3:59])[C:60](=[O:61])[CH3:62].[ClH:16].[F:38][C:39]([CH2:40][N:41]1[CH2:42][CH2:43][CH:44]([NH2:47])[CH2:45][CH2:46]1)([F:48])[F:49].[OH2:63].[OH:28][n:29]1[c:30]2[cH:31][cH:32][cH:33][cH:34][c:35]2[n:36][n:37]1.[c:1]1(-[c:7]2[n:8][cH:9][c:10]([C:13](=[O:14])[OH:15])[cH:11][cH:12]2)[cH:2][cH:3][cH:4][cH:5][cH:6]1>>[c:1]1(-[c:7]2[n:8][cH:9][c:10]([C:13](=[O:15])[NH:47][CH:44]3[CH2:43][CH2:42][N:41]([CH2:40][C:39]([F:38])([F:48])[F:49])[CH2:46][CH2:45]3)[cH:11][cH:12]2)[cH:2][cH:3][cH:4][cH:5][cH:6]1Participants
9
Reactant 8
Product 1
Sources & evidence
- ORD record
- ord-890e6f05fa08488999370e3b47430f73
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (8/10)
Reaction notes
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