Hydrochloric Acid → Quinoxaline-2-carboxylic acid [2-(2,6-dioxopiperidin-3-YL)-1,3-dioxo-2,3-dihydro-1H-isoindol-4-ylmethyl]amide

HRID 317067Notes

Reaction equation

HRID 317067 reaction equation
[C:14]([n:15]1[cH:16][cH:17][n:18][cH:19]1)([n:20]1[cH:21][cH:22][n:23][cH:24]1)=[O:25].[CH3:48][CH2:49][N:50]([CH2:51][CH3:52])[CH2:53][CH3:54].[ClH:26].[NH2:27][CH2:28][c:29]1[c:30]2[c:34]([cH:35][cH:36][cH:37]1)[C:33](=[O:38])[N:32]([CH:39]1[C:40](=[O:46])[NH:41][C:42](=[O:45])[CH2:43][CH2:44]1)[C:31]2=[O:47].[O:55]=[CH:56][N:57]([CH3:58])[CH3:59].[OH2:60].[n:1]1[c:2]([C:11](=[O:12])[OH:13])[cH:3][n:4][c:5]2[cH:6][cH:7][cH:8][cH:9][c:10]12>>[n:1]1[c:2]([C:11](=[O:13])[NH:27][CH2:28][c:29]2[c:30]3[c:34]([cH:35][cH:36][cH:37]2)[C:33](=[O:38])[N:32]([CH:39]2[C:40](=[O:46])[NH:41][C:42](=[O:45])[CH2:43][CH2:44]2)[C:31]3=[O:47])[cH:3][n:4][c:5]2[cH:6][cH:7][cH:8][cH:9][c:10]12

Participants

8

Reactant 7

HCID 313Hydrochloric AcidHCID 962WaterHCID 6228DimethylformamideHCID 8471TriethylamineHCID 682631,1'-CarbonyldiimidazoleHCID 96695Quinoxaline-2-carboxylic acidHCID 219885264-(Aminomethyl)-2-(2,6-dioxopiperidin-3-yl)isoindoline-1,3-dione

Product 1

HCID 58827342Quinoxaline-2-carboxylic acid [2-(2,6-dioxopiperidin-3-YL)-1,3-dioxo-2,3-dihydro-1H-isoindol-4-ylmethyl]amide

Sources & evidence

ORD record
ord-54bc556215f544a58f82a97d182c238b
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (8/10)

Reaction notes

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