Chloride → 2-Fluoro-3-hydroxy-6-[4-(trans-4-pentylcyclohexyl)phenyl]pyridine
Reaction equation
[B:37]([O:38][CH:47]([CH3:48])[CH3:49])([O:39][CH:40]([CH3:41])[CH3:42])[O:43][CH:44]([CH3:45])[CH3:46].[CH2:8]([Li:9])[CH2:10][CH2:11][CH3:12].[CH3:58][CH2:59][CH2:60][CH2:61][CH2:62][CH3:63].[CH:1]([NH:2][CH:3]([CH3:4])[CH3:5])([CH3:6])[CH3:7].[Cl-:52].[ClH:50].[F:13][c:14]1[n:15][c:16](-[c:20]2[cH:21][cH:22][c:23]([CH:26]3[CH2:27][CH2:28][CH:29]([CH2:32][CH2:33][CH2:34][CH2:35][CH3:36])[CH2:30][CH2:31]3)[cH:24][cH:25]2)[cH:17][cH:18][cH:19]1.[Na+:51].[O:53]1[CH2:54][CH2:55][CH2:56][CH2:57]1>>[F:13][c:14]1[n:15][c:16](-[c:20]2[cH:21][cH:22][c:23]([CH:26]3[CH2:27][CH2:28][CH:29]([CH2:32][CH2:33][CH2:34][CH2:35][CH3:36])[CH2:30][CH2:31]3)[cH:24][cH:25]2)[cH:17][cH:18][c:19]1[OH:38]Participants
10
Reactant 9
Product 1
Sources & evidence
- ORD record
- ord-17521277c8b94089a331736efa35b26d
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (8/10)
Reaction notes
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