反应详情

温度

25 °C

To an ice-cold solution of 1.59 g (0.004 mole) of 1-chloro-6-hydroxy-4-nitro-9H-selenoxanthen-9-one in 12 ml of N,N-dimethylformamide with 0.85 ml of diisopropylethyl amine is added 0.85 ml of 2-(diethylaminoethyl)hydrazine. The cooling bath is removed and the mixture is stirred at 25° C. for 2.5 hours. Concentration of the reaction in vacuo leaves an orange solid. Trituration of the solid with boiling 2-propanol gives an orange powder which is dried in vacuo at 80° C. to afford 1.66 g of the dry product as a salt with 1.0 equivalents of hydrogen chloride; mp 255°-257° C. (dec.).

1. customThe cooling bath is removed
2. customConcentration of the reaction in vacuo
3. customleaves an orange solid
4. customis dried in vacuo at 80° C.