Benzaldehyde → HCID 13320884, compound

HRID 381716Notes

Reaction equation

HRID 381716 reaction equation
[CH:1](=O)[C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][CH:3]=1.OS([O-])=O.[Na+].[CH3:14][NH2:15].[C-:16]#[N:17].[K+]>>[CH3:14][NH:15][CH:1]([C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][CH:3]=1)[C:16]#[N:17]

Participants

5

Reactant 4

HCID 240BenzaldehydeHCID 6329MethylamineHCID 9032Potassium CyanideHCID 23665763Sodium Bisulfite

Product 1

HCID 13320884HCID 13320884, compound

Procedure

Benzaldehyde (11 mmol) is added, with stirring, to a solution of NaHSO3 (12 mmol in 4 ml of water). When a white precipitate has formed, 28 ml of an aqueous 25% methylamine solution are added dropwise, and then 12 mmol of potassium cyanide are added at 0° C. The reaction mixture is stirred at room temperature until the reaction is complete. After conventional treatment, the title product is obtained in pure form.

Workup

  1. customWhen a white precipitate has formed

Sources & evidence

ORD record
ord-7b3a757c3747400d81ef8c5a99baeb17
Source dataset
uspto-grants-2001_10
Patent number
US06307068B1

Reaction notes

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