反应详情

122 g of salicylaldehyde 1 and 350 g of potassium carbonate are dissolved in 2L of acetone. While stirring at room temperature, add slowly 165 g of ethyl 4-chloroacetoacetate 2 over a period of 2 hours. When addition is over, stir at reflux for another 4 hours. Cool to room temperature and filter. Wash the filtration cake with 0.5L of acetone. Evaporate the solvent.

1. additionWhen addition
2. stirringstir
3. temperatureat reflux for another 4 hours
4. temperatureCool to room temperature
5. filtrationfilter
6. washWash the filtration cake with 0.5L of acetone
7. customEvaporate the solvent