Hydrochloric Acid → HCID 20283012, compound

HRID 463300Notes

Reaction equation

HRID 463300 reaction equation
[CH2:1]([NH:17][C:18]([C:20]1[CH:29]=[C:28]([O:30][C:31]2[CH:36]=[CH:35][CH:34]=[CH:33][C:32]=2[N+:37]([O-])=O)[C:27]2[C:22](=[CH:23][CH:24]=[CH:25][CH:26]=2)[C:21]=1[OH:40])=[O:19])[CH2:2][CH2:3][CH2:4][CH2:5][CH2:6][CH2:7][CH2:8][CH2:9][CH2:10][CH2:11][CH2:12][CH2:13][CH2:14][CH2:15][CH3:16].Cl>C(O)(C)C.[Fe]>[OH-:19].[NH2:37][C:32]1[CH:33]=[CH:34][CH:35]=[CH:36][C:31]=1[O:30][C:28]1[C:27]2[C:22](=[CH:23][CH:24]=[CH:25][CH:26]=2)[C:21]([OH:40])=[C:20]([C:18](=[O:19])[NH:17][CH2:1][CH2:2][CH2:3][CH2:4][CH2:5][CH2:6][CH2:7][CH2:8][CH2:9][CH2:10][CH2:11][CH2:12][CH2:13][CH2:14][CH2:15][CH3:16])[CH:29]=1

Participants

5

Reactant 2

HCID 313Hydrochloric AcidHCID 20283020HCID 20283020, compound

Product 1

HCID 20283012HCID 20283012, compoundYield 118.8%

Reagents, catalysts & solvents 2

HCID 23925IronCatalystHCID 3776IsopropanolSolvent

Procedure

The thus obtained 2-hexadecylcarbamoyl-4-(2-nitrophenoxy)-1-naphthol (10 g) was reduced with iron in isopropanol. The reaction mixture was filtered, condensed under reduced pressure and added with concentrated hydrochloric acid, and precipitated crystals were collected by a filtration to give 5.8 g of 4-(2-aminophenoxy)-2-hexadecylcarbamoyl-1-naphthol hydroxide. Yield: 57%.

Workup

  1. filtrationThe reaction mixture was filtered
  2. customcondensed under reduced pressure
  3. customprecipitated crystals
  4. filtrationwere collected by a filtration

Sources & evidence

ORD record
ord-4ecf249b607d43aab845f2f968da32e3
Source dataset
uspto-grants-1985_05
Patent number
US04518682

Reaction notes

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