反应详情

温度

80 °C

5.0 g (28.9 mmol) 4-bromophenol, 3.93 g (43.4 mmol) (chloromethyl)cyclopropane and 7.99 g (57.8 mmol) K2CO3 are added to 10 mL DMF and stirred at 80° C. over night. Afterwards the reaction mixture is diluted with water and extracted with DCM. The organic layer is dried with MgSO4, filtered and the solvent is removed in vacuo.

1. extractionextracted with DCM
2. dry with materialThe organic layer is dried with MgSO4
3. filtrationfiltered
4. customthe solvent is removed in vacuo