huagongshe.com
HRID51871

反应详情

EQUATION

反应方程式

HRID 51871 的结构方程式

REACTANTS

反应物

6
结构：O=C(O)c1ccc(F)cc1
HCID9973

Benzoic acid, 4-fluoro-

C7H5FO2

结构：O=C([O-])[O-].[K+].[K+]
HCID11430

Potassium Carbonate

CK2O3

结构：CCN(C(C)C)C(C)C
HCID81531

Diisopropylethylamine

C8H19N

结构：Br.BrCc1ccccn1
HCID2734720

2-(Bromomethyl)pyridine hydrobromide

C6H7Br2N

结构：CN(C)C(On1nnc2cccnc21)=[N+](C)C.F[P-](F)(F)(F)(F)F
HCID9886157

Methanaminium, N-((dimethylamino)(3H-1,2,3-triazolo(4,5-b)pyridin-3-yloxy)methylene)-N-methyl-, hexafluorophosphate(1-) (1:1)

C10H15F6N6OP

结构：CNc1ccc(OC)c2nc(N)sc12
HCID22736978

未命名化合物

PRODUCTS

生成物

1
结构：COc1ccc(N(C)Cc2ccccn2)c2sc(NC(=O)c3ccc(F)cc3)nc12
HCID22736983

未命名化合物

AUXILIARIES

试剂、催化剂与溶剂

2
结构：CN(C)C=O
溶剂HCID6228

N,N-Dimethylformamide

C3H7NO

结构：C1CCOC1
溶剂HCID8028

Tetrahydrofuran

C4H8O

PROCEDURE

实验过程

From 4-methoxy-N7-methyl-benzothiazole-2,7-diamine with potassium carbonate and 2-(bromomethyl)pyridine hydrobromide in DMF, then treatment with 4-fluoro-benzoic acid, HATU and N-ethyldiisopropylamine in THF. ES-MS m/e (%): 423 (M+H+, 100).